Endocrine Abstracts

Background: Kidney diseases and cardiac diseases can affect each other. Patient with renal failure have many cardiac problems specially heart failure, anemia of CRF is resistant to treatment with iron or even blood transfusion and erythropoietin therapy gives good results as the failing kidney can not synthesize itThe previous published data showed that EPO treatment in patients with cardiorenal syndrome (CRS) anemia led to reverse ventricular remodeling...

Vitamin D deficiency has become a worldwide problem, although vitamin D deficiency had associated with increased insulin resistance, obesity and HbA1c in patients with T2D.It is uncertain whether vitamin D deficiency causes diabetes or its due to confounding. The active metabolite 1α,25-dihydroxyvitamin D3 may affect the receptors of pancreatic β-cells and hence affect insulin secretion, also it may have impact on insulin sensitivity.<p cla...

According to the seventh edition of diabetes atlas, 415 million persons all over the world are diabetics requiring more than 680 billion US $ annually for their management. Diabetes affects middle and low socio economic countries than developed countries. The ADA/EASD guidelines included drug price as one of the criteria to choose from different classes. Incretin based therapy are new classes for treatment of T2 DM with low incidence of hypoglycemia and modest weight loss, but...

Background: It was noted in the last few years there was an increased incidence of vasculitis and vasculitic reactions in patients with thyrotoxicosis. Those vasculitic reactions ranged from simple purpuric skin lesion to sever intra-alveolar hemorrhage and even to Steven Johnson Syndrome, Most of those vasculitic reactions occurred in patients receiving propylthiouracil or methimazole. But many other cases were detected in thyrotoxic patients even be...

Background: Hepatitis C virus is common in Egypt and its prevalence varies from 10 to 17%. Beside its harmful effect on the liver, it can lead to variable other effects on various organs and tissues known as the extrahepatic manifestations of HCV. hepatitis C virus induced thyroid diseases in the form of thyroiditis resulting in hypofunction or even hyperfunction of the gland. thyroid disease was found to be of immune nature. Also diabetes which is often termed hepatogenous di...

Back ground and objectives: Relation between thyroid function with respect to insulin resistance has been a field that is rich and captivating for research and further examination. Few studies have suggested that metformin, the first-line in diabetes management, may lower thyroid-stimu-lating hormone (TSH). Owing to Paucity of studies regarding the effect of metformin on TSH in hypothyroidism patients, this study compares the effect of metformin on TSH and BMI in Egyptian na&#...

Background: Fasting during Ramadan is an obligatory duty for all healthy adult Muslims. However, a lot of type 2 diabetic Muslim patients insist on fasting whatever their condition. There are several potential physiological benefits from fasting, but the prolonged fasting hours during summer provides many questions about safety and efficacy of different insulin regimens for treatment of type 2 diabetic patients during Ramadan. So we aimed in this study is to assess safety and ...

Introduction: Fasting in Ramadan is one of the five pillars of Islam. Without relevant medical advice and intervention, fasting can put patients with T2DM at an increased risk of serious complications. The aim of this study was to compare the effectiveness and safety of available oral anti diabetic drugs in treating type-2 diabetics during Ramadan fasting.Methods: More than 400 T2DM patients were included in this 16-week prospective study, data were coll...